Bromelain Treatment Leads to Maturation of Monocyte-derived Dendritic Cells but Cannot Replace PGE2 in a Cocktail of IL-1β, IL-6, TNF-α and PGE2
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چکیده
منابع مشابه
Effect of Ibuprofen on IL-1β, TNF-α and PGE2 Levels in Periapical Exudates: A Double Blinded Clinical Trial
Background: Bone resorption is one of the main features of inflammatory periapical lesions and is mainly mediated by interleukin-1 beta (IL-1β), tumor necrosis factoralpha (TNF-α) and prostaglandin-E2 (PGE2). Recent investigations of these lesions revealed that pharmacological modulation may be possible. Objective: The aim of this study was to evaluate the effect of Ibuprofen on IL-1β, TNF-α an...
متن کاملThe Effect of Monophosphoryl Lipid A on Maturation of DCs from Patients with Acute Myeloid Leukaemia
Background: Generation of monocyte-derived dendritic cells (MDDC) is induced in the presence of GM-CSF and IL-4, and a maturation stimulus is added to the monocyte culture to obtain mature Dendritic Cells (DCs) suitable for therapy. TNF-α is the most common cytokine used for activating DCs and generating mature MDDC either alone or in combination with other cytokines. Objective: To compare effe...
متن کاملeffect of ibuprofen on il-1β, tnf-α and pge2 levels in periapical exudates: a double blinded clinical trial
background: bone resorption is one of the main features of inflammatory periapical lesions and is mainly mediated by interleukin-1 beta (il-1β), tumor necrosis factoralpha (tnf-α) and prostaglandin-e2 (pge2). recent investigations of these lesions revealed that pharmacological modulation may be possible. objective: the aim of this study was to evaluate the effect of ibuprofen on il-1β, tnf-α an...
متن کاملIn vitro assesment of anti-inflammatory activities of coumarin and Indonesian cassia extract in RAW264.7 murine macrophage cell line
Objective(s): Inflammation is an immune response toward injuries. Although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, Alzheimer’s and various cancer. Indonesian cassia (Cinnamomum burmanni C. Nees & T. Ness) known to contain coumarin, is widely used for alternative medicine es...
متن کاملDifferential inflammasome expression and IL-1β secretion in monocyte-derived dendritic cells differentiated with IL-4 or IFN-α
BACKGROUND NLRP3-inflammasome activation was evaluated in monocyte-derived dendritic cells (DC) obtained through IL-4 (IL4-DC) or IFN-α (IFN-DC) protocols and pulsed with chemically inactivated HIV-1. Inflammasome' genes expression and IL-1β secretion were compared in DC isolated from 15 healthy subjects (HC) and 10 HIV-1 infected individuals (HIV+). FINDINGS Whether HIV was able to increased...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Immunology
سال: 2011
ISSN: 0300-9475
DOI: 10.1111/j.1365-3083.2011.02562.x